Development Of An Aptamer-Based MRI Contrast Agent For Thrombin Detection1
نویسندگان
چکیده
منابع مشابه
Hydrothermal Synthesis of an Ethiodol Based Ferrofluid as a Potential MRI Contrast Agent
In the present work, stable ferrofluids containing oleic acid capped magnetite nanoparticles were synthesized via low temperature hydrothermal method. The physical and chemical properties of the synthesized particles were studied using TEM, XRD, AFM, VSM and PCS techniques. Mean particles size of the samples was between 4.5 and 10 nanometers, depending on experimental conditions. Effect ...
متن کاملdevelopment and implementation of an optimized control strategy for induction machine in an electric vehicle
in the area of automotive engineering there is a tendency to more electrification of power train. in this work control of an induction machine for the application of electric vehicle is investigated. through the changing operating point of the machine, adapting the rotor magnetization current seems to be useful to increase the machines efficiency. in the literature there are many approaches wh...
15 صفحه اولA novel MRI contrast agent synthesized by ion exchange method
Objective: In this study, the zeolite-coated iron oxide nanoparticles were evaluated as MRI contrast agent and effect of the nanocomposite synthesis method on MRI contrast was tested. Materials and Methods: Ion exchange method was used for synthesis of iron oxide-zeolite and the as prepared nanocomposite was characterized by XRD, FESEM and TEM. The nanocomposite toxicity in the cell culture, a...
متن کاملAptamer-based SERRS sensor for thrombin detection.
We describe an aptamer-based surface enhanced resonance Raman scattering (SERRS) sensor with high sensitivity, specificity, and stability for the detection of a coagulation protein, human alpha-thrombin. The sensor achieves high sensitivity and a limit of detection of 100 pM by monitoring the SERRS signal change upon the single-step of thrombin binding to immobilized thrombin binding aptamer. T...
متن کاملAptamer Based Microsphere Biosensor for Thrombin Detection
We have developed an optical microsphere resonator biosensor using aptamer as receptor for the measurement of the important biomolecule thrombin. The sphere surface is modified with anti-thrombin aptamer, which has excellent binding affinity and selectivity for thrombin. Binding of the thrombin at the sphere surface is monitored by the spectral position of the microsphere’s whispering gallery m...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Canadian Young Scientist Journal
سال: 2013
ISSN: 1913-1925,2291-6954
DOI: 10.13034/cysj-2013-003